Delete specific entries from a column [duplicate] - mysql

This question already has answers here:
Mysql remove the specific word in comma seperated string
(6 answers)
Is storing a delimited list in a database column really that bad?
(10 answers)
Closed 5 years ago.
I already read the mysql wiki but didn't get an answer how to delete specific entries from all rows in a column.
Let's say there's a column Example.
In Example the .php wrote: "One, Two, Three, Four, Five, Six"
And you want to delete Two and Six in all rows of the column.
I don't get it how to delete those entries without having multiple commas. (Multiple commas = "One,, Three")
Thanks in Advance

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Need to remove numeric data from row in MySQL [duplicate]

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I have millions of data in MySQL table, now I need to update one particular column of the table with only non-numeric characters. That is I need to remove all numbers from that column. The row wont be deleted, only updated with only non-numeric values.
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